The study's authors observed that this reduction in microRNA-210 was responsible for alterations in specific vascular protein levels and impaired blood vessel endothelial cell function.
Furthermore, in laboratory experiments, restoration of microRNA-210 levels in red blood cells helped prevent the development of vascular injury through specific molecular changes.
“The findings demonstrate a previously unrecognized cause of vascular injury in type 2 diabetes,” said Zhichao Zhou, researcher at the department of medicine, Solna, Karolinska Institutet, Sweden, in a press release. “We hope that the results will pave the way for new therapies that increase red blood cell microRNA-210 levels and thereby prevent vascular injury in patients with type 2 diabetes.”
Read the full study here.
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November 12, 2021 at 04:55AM
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We may finally know why type 2 diabetes is associated with vascular damage - Cardiovascular Business
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