These type 2 diabetes medications reduce the risk of atrial fibrillation - Cardiovascular Business

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Overall, GLP-1RAs and SGLT-2 inhibitors were associated with a substantial decrease in a patient’s risk of developing AFib. For GLP-1RAs, the decrease in risk was equal to 14%. For SGLT-2 inhibitors, the decrease in risk was equal to 19%.

A much smaller decrease—equal to 7%—was associated with DPP-4 inhibitors.

“Collectively, newer antidiabetics do not confer an increased risk for AF among patients with type 2 diabetes mellitus, while SGLT-2 inhibitors and GLP-1RAs seem to be protective, providing an additional cardiovascular benefit, besides the well-established ones,” wrote lead author Dimitrios Patoulias, MD, Aristotle University of Thessaloniki in Greece, and colleagues. “These observations might have direct treatment implications, especially for those patients having additional risk factors for AF except for type 2 diabetes mellitus, such as valvular disease.”

The full analysis is available here.

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These type 2 diabetes medications reduce the risk of atrial fibrillation - Cardiovascular Business
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